Tapestri Platform Cell and Gene Therapy Solutions

This flyer details Mission Bio’s Cell & Gene Therapy Assay Services, which utilize the Tapestri® single-cell multiomic platform to eliminate the ambiguity of fragmented QC workflows. By simultaneously mapping genotype, gene expression, and phenotype at the single-cell level, developers can definitively evaluate Critical Quality Attributes (CQAs) like vector copy number, multiplex gene editing editing co-occurrence for on-/off-targets, rare genotoxicity events, and evaluate biodistribution. This high-resolution approach unmasks dangerous cell product heterogeneity and in vivo gene therapy safety assessments missed by standard assays. Ultimately, these GxP-ready, transferable solutions provide the indisputable comparability and safety data required to meet evolving FDA Chemistry, Manufacturing, and Controls (CMC) guidelines, de-risking in vivo and ex vivo therapy programs confidently.