AMP 2018

October 31 – November 3
Henry B. Gonzalez Convention Center
San Antonio, Texas

Booth 705

 

Wednesday, October 31 – Corporate Workshop, 4:00 – 4:50 pm, Room 214A

Jerald Radich, Professor, University of Washington School of Medicine  – Understanding Response, Resistance, and Relapse through Single-Cell DNA Analysis

Dennis Eastburn, CSO, Mission Bio – Moving from Bulk NGS to Precision Sequencing with Single-Cell Genomics: Resolving Heterogeneity in Blood and Solid Tumors

The average read-out from conventional bulk (NGS) sequencing misses the rare events and underlying genetic diversity within and across cell populations. To improve patient stratification, therapy selection, and disease monitoring, we need insights into clonal evolution and mutation co-occurrence within every single cell. The Tapestri Precision Genomics Platform enables precision sequencing with the sensitive and unambiguous identification of multiple co-occurring mutations within subclones that drive disease and is not possible with bulk NGS measurements. In this workshop, you will hear from translational and pathology labs characterizing heterogeneity with mutational signatures at the single-cell level to move precision medicine forward, and will include:

– Tapestri overview

– Managing minimal residual disease for AML

– Clonal analysis of solid tumor metastases

Register here to hold your spot!


Friday, November 2 – Oral Presentation by Mission Bio CSO, Dennis Eastburn, PhD., Room 214, Meeting Level

Longitudinal Monitoring of AML Tumors with High-throughput Single-Cell DNA Sequencing Reveals Rare Clones Prognostic for Disease Progression and Therapy Response

10:45 – 11:45 am  

Session Title: Hematopathology Platform Presentations
Abstract # 16418
Poster # H041


Saturday, November 3 – Poster Presentation by Mission Bio CSO, Dennis Eastburn, PhD.

Longitudinal Monitoring of AML Tumors with High-throughput Single-Cell DNA Sequencing Reveals Rare Clones Prognostic for Disease Progression and Therapy Response

9:45 – 10:45 am  

Poster # H041